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Psychedelics Rehab Centers

Browse 38 of the best treatment centers for psychedelic use and related mental health concerns. Explore our curated list of facilities offering virtual care, outpatient programs, and luxury residential treatment. Read unbiased reviews and filter by insurance, location, and level of care to find the treatment center that best supports your recovery needs.
Psychedelics Treatment

Top Psychedelics Treatment Programs

Residential
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Key Healthcare

  • 5.0 (4)
  • 6270 Zumirez Dr, Malibu, California, 90265
  • Insurance Accepted
Residential
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Vanity Wellness Center

  • 5.0 (8)
  • 19935 Ventura Blvd First Floor, Woodland Hills, California, 91364
  • Insurance Accepted
Residential
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Safe Haven Recovery

  • 5.0 (8)
  • 1690 Coldwater Canyon Dr, Beverly Hills, California, 90210
  • Insurance Accepted
Residential
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Bradford at Madison

  • 5.0 (8)
  • 1600 Browns Ferry Rd, Madison, Alabama, 35758
  • Insurance Accepted
Residential
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Harmony Place

  • 5.0 (12)
  • 23041 Hatteras St, Woodland Hills, California, 91367
  • Insurance Accepted
Residential
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Seasons in Malibu

  • 3.9 (7)
  • 7055 Birdview Ave, Malibu, California, 90265
  • Insurance Accepted
Residential
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Altus Rehab

  • 5.0 (7)
  • 18084 Rancho St., Los Angeles, California, 91316
  • Insurance Accepted

More About Psychedelics Treatment Centers

Psychedelic drugs—also known as hallucinogens—are substances that alter perception, mood, consciousness, and sensory awareness. These drugs can dramatically change how you think, feel, and experience your environment. Psychedelics include both synthetic hallucinogens (such as LSD and MDMA) and naturally occurring psychedelics (such as psilocybin mushrooms and mescaline from peyote cactus).

Common Types of Psychedelic Drugs

Some of the most widely used psychedelic substances include:

  • LSD (Acid) – a powerful synthetic hallucinogen.
  • Mescaline – a natural psychedelic from peyote and other cacti.
  • Psilocybin Mushrooms – also known as “magic mushrooms” or “shrooms.”
  • Ketamine – a dissociative anesthetic with hallucinogenic effects.
  • MDMA (Ecstasy/Molly) – a psychoactive stimulant with empathogenic effects.

How Psychedelic Drugs Affect the Brain

Psychedelics work by altering neurotransmitter activity—primarily serotonin, dopamine, and glutamate. These neurotransmitters regulate:

  • Mood
  • Sensory perception
  • Sleep
  • Appetite
  • Emotional processing
  • Cognition

By binding to serotonin (5-HT2A) receptors, psychedelics can create a state of neuroplasticity, increasing sensory awareness, emotional openness, creativity, and altered thinking.

This heightened brain connectivity is why psychedelics are being studied for potential therapeutic use—but it also increases the risk for psychological distress, bad trips, and long-term mental health complications.

Short-Term Effects of Psychedelics

Psychedelics affect each person differently. Common short-term effects include:

Physical Effects

  • Dilated pupils
  • Elevated heart rate
  • Changes in body temperature
  • Tremors or muscle tension

Psychological & Emotional Effects

  • Euphoria
  • Heightened empathy
  • Enhanced creativity
  • Spiritual or mystical experiences
  • Anxiety or panic attacks
  • Confusion or paranoia

Perceptual Changes

  • Distorted sense of time
  • Vivid colors, sounds, or patterns
  • Hallucinations (visual, auditory, tactile)
  • Dissociation from reality

Are Psychedelics Addictive?

Psychedelics are generally considered less physically addictive than substances like opioids, alcohol, or stimulants. However, behavioral addiction and psychological dependence can still occur—especially when psychedelics are used:

  • To escape reality
  • To self-medicate emotional pain
  • To cope with trauma
  • To manage depression or anxiety
  • To repeat intense spiritual or euphoric experiences

Repeated psychedelic use can also lead to tolerance, meaning higher doses are needed to feel the same effects—a major risk factor for problematic use.

Do I Need Rehab for Psychedelic Addiction?

You may benefit from psychedelic addiction treatment if you notice:

  • Loss of control over your use
  • Increasing dosage to achieve the same effect
  • Psychological dependence
  • Anxiety, paranoia, or depression after use
  • Strained relationships or isolation
  • Use interfering with work, school, or responsibilities
  • Hallucinogen Persisting Perception Disorder (HPPD)
  • Psychotic symptoms or mental health decline

If any of these resonate, it’s important to consult a mental health or addiction specialist.

Questions to Ask Your Provider

When speaking with a doctor or therapist about psychedelic misuse, consider asking:

  • What are the signs of psychedelic addiction?
  • What treatment programs are recommended for hallucinogen abuse?
  • Do I need dual-diagnosis treatment for co-occurring mental health issues?
  • Are there risks of long-term brain changes from LSD or psilocybin?
  • What does recovery look like after psychedelic addiction?

Levels of Care for Psychedelic Addiction Treatment

While psychedelics don’t cause physical withdrawal like opioids or alcohol, psychological symptoms can be severe and require professional treatment.

Available treatment levels include:

1. Inpatient Rehab

  • 24/7 medical and mental health monitoring
  • Safe environment for stabilization

2. Residential Treatment

  • 28+ days of structured therapy
  • Peer support and daily therapeutic programming

3. Partial Hospitalization Program (PHP)

  • 5–7 days/week, full-day treatment
  • Ideal for severe psychological symptoms

4. Intensive Outpatient Program (IOP)

  • 3–5 days/week, several hours a day
  • Flexibility while receiving structured care

5. Outpatient Therapy

  • Weekly sessions
  • For mild addiction or aftercare

If you have symptoms of depression, anxiety, PTSD, or psychosis, look for a rehab offering dual diagnosis treatment.

Therapies Used in Psychedelic Addiction Rehab

Evidence-based treatments may include:

Combined, these therapies help you regain control, reduce cravings, and process emotional issues that may contribute to psychedelic misuse.

Finding Help for Psychedelic Addiction

Supportive resources include:

  • Rehabs for psychedelic addiction
  • Telehealth therapy
  • Psychedelic harm-reduction counseling
  • Support groups
  • Trusted family or friends
  • Primary care physicians

If you feel out of control, overwhelmed, or concerned about your use, reaching out is the first step toward healing.

Psychedelics Treatment Frequently Asked Questions

Psychedelics are hallucinogenic substances—such as LSD, MDMA, ketamine, mescaline, and psilocybin mushrooms—that alter perception, mood, and thinking. They work by interacting with serotonin, dopamine, and glutamate receptors, which can change sensory processing, cognition, and emotional regulation.

While psychedelics are generally considered less physically addictive than opioids or stimulants, psychological addiction can occur—especially if someone uses them to escape stress, trauma, or emotional pain. Tolerance also builds quickly, which can lead to escalating use.

Signs of psychedelic misuse include increased tolerance, loss of control, using more frequently than intended, anxiety or paranoia after use, relationship problems, impaired functioning, and cravings to escape reality.

Heavy or frequent use can trigger anxiety, panic attacks, drug-induced psychosis, flashbacks, paranoia, depression, or dissociation—especially in people with pre-existing mental health conditions.

There is no traditional physical withdrawal, but many people experience emotional or psychological withdrawal such as mood swings, irritability, cravings, anxiety, sleep changes, and difficulty feeling grounded.

Rehab is recommended if psychedelic use causes loss of control, increased tolerance, mental health decline, strained relationships, job issues, or if you continue using despite negative consequences.

Treatment options include inpatient rehab, residential programs, partial hospitalization (PHP), intensive outpatient (IOP), and outpatient therapy. Most programs use evidence-based therapies like CBT, DBT, trauma-informed therapy, relapse-prevention planning, and dual-diagnosis treatment.

Yes. Dual-diagnosis treatment centers specialize in treating both substance use and mental health conditions—such as anxiety, depression, trauma, or psychosis—at the same time for better long-term outcomes.

The length varies by level of care. Inpatient treatment typically lasts 28–60 days, PHP and IOP last several weeks to months, and outpatient care may continue for ongoing support.

Yes. Repeated or high-dose use can lead to persistent anxiety, paranoia, flashbacks (HPPD), impaired concentration, memory issues, mood instability, or psychotic episodes—especially in vulnerable individuals.

Cognitive Behavioral Therapy (CBT), Dialectical Behavior Therapy (DBT), Motivational Interviewing (MI), trauma therapy, mindfulness-based approaches, and relapse-prevention planning are the most effective evidence-based methods.

Inpatient or residential rehab is recommended for severe symptoms, co-occurring disorders, or unsafe environments. Outpatient programs are suitable for mild to moderate cases or for continued support after inpatient care.
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